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Weight loss and Health Management: Your Guide to a healthy New Year!!

Weight Loss and Health Management: A Guide to a Healthy New Year!

DB2 Weight Loss and Health Management Guide

DB2 recognizes that managing one's weight is crucial to maintaining good health and well-being. Our newest medications, Semaglutide and Tirzepatide, have shown impressive results in weight management.

 1. Understanding Semaglutide

Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, acts on the hypothalamus to reduce appetite and food intake while increasing feelings of fullness. In clinical trials like the STEP trials, Semaglutide has demonstrated substantial weight loss results, with participants achieving an average weight reduction of 15.8kg or 34.7lbs over 68 weeks. The FDA-approved dose for weight loss is .25mg – 2.4mg once weekly through subcutaneous injection. However, some potential side effects like nausea, vomiting, and diarrhea might occur, particularly during initial usage.


2. Exploring Tirzepatide

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, targeting multiple pathways involved in glucose and weight regulation. Studies, including SURPASS trials, have shown Tirzepatide's effectiveness, yielding total mean weight loss of 26.6% (29.2 kg or 64.4 lb.) from study entry over 84 weeks. Participants on placebo achieved a total mean weight loss of 3.8% (4.1 kg or 9.0 lb.) from study entry over 84 weeks. The FDA-approved dosing regimen for weight management is 2.5 mg – 15mg, administered weekly via subcutaneous injection. Side effects may include gastrointestinal disturbances, although generally, they tend to diminish over time.

 3. Efficacy and Safety

Comparing both medications, Semaglutide and Tirzepatide, demonstrates similar efficacy in promoting weight loss. However, individual responses may vary. Regarding safety, both medications have shown generally well-tolerated profiles, with gastrointestinal side effects being the most common. Semaglutide might have a slightly higher incidence of nausea during the initial phase compared to Tirzepatide. Despite the safety of these medications DB2 stresses the importance of being evaluated by a medical professional and seeking medical supervision on your weight loss journey.

 4. Patient Considerations and Recommendations

At DB2 our providers consider various factors when prescribing Semaglutide or Tirzepatide, including a patient's medical history, existing conditions, and potential drug interactions. Patients must be educated about the benefits and potential side effects of these medications. Including, the cost, availability and administration by injection. Additionally, it's vital to emphasize the role of lifestyle modifications, exercise, and a balanced diet alongside medication for optimal weight management. If you are confused about engaging a trainer, nutritional expert or a health coach…DB2 has connections for you.

 5. Future Directions and Conclusion

Ongoing research continues to explore the long-term effects, safety, and potential combination therapies involving Semaglutide, Tirzepatide and other weight loss treatments. These medications offer hope for individuals struggling with obesity, but their use should be a part of a comprehensive medically managed weight loss plan. DB2s Doctor and Medical team are dedicated to helping you transform your life and restore your hope for a better quality of life. Consulting a healthcare professional is crucial before starting any new medication regimen. Call DB2 Regeneration Clinic today 636 265-2822 or book a appointment on line at


We partner with the best to ensure every possible tool for success.

Dr. Devin Bell, DO

  • Dr. Devin Bell, DO -As a board-certified Family Practice physician with expertise in regenerative medicine, I have a strong background in the field. I obtained my Bachelor's Degree in biology from Westminster College in Fulton, Missouri, and pursued my medical education at Kansas City University of Medicine and Biosciences in Kansas City, Missouri. Following that, I completed my residency in Family Practice through Deaconess Health Systems in Evansville, Indiana.

Doug Bouldin, FNP

  • Doug Bouldin, FNP -Doug Bouldin is a Board Certified Family Nurse Practitioner and Co-Founder of DB2 Regeneration. Doug has been practicing as a Family Nurse Practitioner for more than 25 years across the state of Missouri. 

Bouldin has been a leader amongst his peers, presenting at several conferences and symposiums over the course of his career. He carries a passion for education and is excited about the opportunity to pass it on to patients who have never heard of PRP and Cellular treatments. Among his primary goals for DB2 Regeneration is to provide St Charles County and the greater St Louis community with, “the highest quality Regenerative Medicine with innovation and compassion.”

Dr. Ron Patrick, DC, MS

  • Dr. Ron Patrick, DC,MS -

 a passionate and dedicated Doctor of Chiropractic with over 12 years of experience in the field. Alongside my chiropractic expertise, I hold a Master's degree in Sports Science and Rehabilitation, allowing me to provide comprehensive care for patients seeking optimal physical performance and pain management.

My journey began at Logan College of Chiropractic, where I graduated with my Doctor of Chiropractic degree in 2010, and shortly thereafter obtained my Master's in 2011. Since then, I've had the privilege of practicing in integrated multidisciplinary medical, chiropractic, and physical therapy settings. My focus lies in specialized areas such as pain management, physical medicine, personal injury, and regenerative medicine.

  • Certified in Manipulation Under Anesthesia: a powerful technique that allows me to address complex musculoskeletal issues with utmost precision and efficacy.

  • Certificated in ART (Active Release Technique) further reinforce my commitment to delivering cutting-edge treatments for my patients.

Check out one of our many affiliates:


Health Management Program

Our unique membership model, similar to Concierge Medicine, provides you with the best options at DB2. While it's not mandatory, we advise you to consider this membership to receive the most favorable pricing for our services. You'll also have access to personalized medical management tailored precisely to your requirements and direct access to your doctor's phone line.

We understand the frustration that comes with a broken system, and we know you do too. It's not that doctors lack empathy, but rather, the flawed system that creates disillusionment.

Please feel free to share with anyone you believe could benefit from our services.

We thank you.

Local Medical Clinic serving the

Lake St Louis, St Louis, Wentzville, Troy, O'Fallon

and surrounding areas. 


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