Introduction:
Degenerative disc disease (DDD) affecting the cervical and lumbar spine is
a common cause of chronic pain and disability. Traditional treatments often focus on
managing symptoms rather than addressing the underlying degeneration. However,
emerging regenerative medicine techniques such as Platelet-Rich Plasma (PRP) and
Stem Cell therapy offer promising alternatives by targeting tissue repair and
regeneration. In this article, we delve into the potential of PRP and Stem Cell therapy in
managing disc degenerations.
Understanding Disc Degeneration:
Disc degeneration involves the breakdown of the
intervertebral discs, leading to decreased disc height, loss of hydration, and structural
changes. This process contributes to pain, stiffness, and reduced mobility in affected
individuals. Conventional treatments like medication, physical therapy, and surgery may
provide symptomatic relief but often fail to address the underlying degeneration.
Platelet-Rich Plasma (PRP): PRP therapy involves the injection of concentrated
platelets derived from the patient's blood into the affected area. Platelets contain growth
factors and cytokines that promote tissue repair and regeneration. Several studies have
explored the efficacy of PRP in treating disc degeneration.
A study by Tuakli-Wosornu et al. (2016) demonstrated that intradiscal PRP injections
led to significant improvements in pain and function scores for patients with
symptomatic disc degeneration. Another study by Levi et al. (2019) reported
improvements in pain and disability scores following PRP injections in patients with
lumbar disc degeneration.
Stem Cell Therapy:
Stem cell therapy involves the transplantation of stem cells, either
from the patient's own body or from a donor, into the damaged tissue to facilitate repair
and regeneration. Mesenchymal stem cells (MSCs) are of particular interest due to their
ability to differentiate into various cell types and modulate the immune response.
Research into stem cell therapy for disc degeneration is ongoing, with promising results.
A study by Orozco et al. (2011) found that intradiscal injection of autologous MSCs
resulted in improvements in pain and disability scores for patients with chronic disc
degeneration. Similarly, a study by Centeno et al. (2017) reported improvements in pain
and function following intradiscal injection of bone marrow-derived stem cells.
At DB2 Regeneration, we go beyond merely offering therapies. We seamlessly integrate
them into our comprehensive 360-degree approach, leveraging cutting-edge, evidence-
based rehabilitation strategies for enhancing strength, stability, and proprioception. Our
services extend to include chiropractic adjustments to optimize joint motion, along with
non-invasive spinal decompression utilizing state-of-the-art computerized technology,
aimed at alleviating pain and restoring mobility. This is the DB2 difference – a fusion of
services dedicated to enhancing your quality of life.
Conclusion:
Platelet-Rich Plasma (PRP) and Stem Cell therapy represent innovative
approaches to addressing cervical and lumbar spine disc degenerations. While further
research is always valuable, we know now these therapies offer long-term efficacy and
safety, based on current evidence. If you or a family member have suffered from neck
pain or low back pain associated with degenerative disc disease, DB2 invites you
schedule an appointment. Check out our integrated non-surgical approach to disc
disease, isn’t it time you or your loved one to find real solutions to pain without
controlled substances? Call 636 265-2822 or go to DB2regeneration.com
References:
1. Tuakli-Wosornu YA, Terry A, Boachie-Adjei K, et al. Lumbar Intradiskal Platelet-
Rich Plasma (PRP) Injections: A Prospective, Double-Blind, Randomized
Controlled Study. PM&R. 2016;8(1):1-10.
2. Levi D, Horn S, Tyszko S, Levin J, Hecht-Leavitt C, Walko E. Intradiscal platelet-
rich plasma injection for chronic discogenic low back pain: preliminary results
from a prospective trial. Pain Med. 2019;20(11):2241-2247.
3. Orozco L, Soler R, Morera C, Alberca M, Sánchez A, García-Sancho J.
Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot
study. Transplantation. 2011;92(7):822-828.
4. Centeno CJ, Markle J, Dodson E, et al. Treatment of lumbar degenerative disc
disease-associated radicular pain with culture-expanded autologous
mesenchymal stem cells: a pilot study on safety and efficacy. J Transl Med.
2017;15(1):197.
Comments